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Peter Tabichi teaches science to schoolchildren in Keriko, Kenya, a region frequently blighted by drought and famine. His students come from very poor families, many having to go without adequate food at home. It's an often bleak landscape, and drug abuse, early school dropout and suicide are all too common.

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Though difficult for most of us to even imagine, it's a reality for tens of millions of impoverished kids around the world: living every day without shoes on your feet. In India, it's shockingly common to see shoeless infants and toddlers, an obvious health risk that can lead to infections like hookworm and even elephantiasis.

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When Mohan Sudabattula was volunteering in the prosthetic department of a Utah hospital, he noticed that medical rehab equipment like crutches and wheelchairs tended to have a short life: that is, it was typically used by one person, then thrown away.

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Last year, bicycle-sharing startup oBike ceased operations in Singapore, leaving the city with an inconvenient parting gift: thousands of abandoned bicycles, left behind in parks and other public spaces.

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Just before her seventh birthday, Jenny Shaw was diagnosed with kidney cancer. The doctors told her and her stricken parents that the tumor had metastasized to Jenny's liver, and would require chemotherapy, radiation and surgery.

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A 22-year-old entrepreneur in New Jersey is challenging attitudes around the abilities of people with Down’s Syndrome, and he’s doing it by leading by example: John Cronin, who himself has the chromosomal condition, is the co-founder of multimillion-dollar startup John’s Crazy Socks.

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Without question, working with homeless youth is not for the weak of heart. Remarkably, Deborah Shore has been doing it for forty-five years, in one of the nation's toughest urban markets: Washington D.C. Raised on union songs in Pittsburgh, PA, Shore began working with young people at the outset of her career, and has never looked back.

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Growing up in Ann Arbor, Michigan, Aisha Bowe was the child of divorce, and dealt with many of the issues that come with the territory. She had a lack of self-esteem and scholastic problems that led to less-than-stellar grades, excluding her from consideration at a top school. But she soldiered on at community college, and there she met a teacher who challenged her to reconsider her gifts.

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Growing up as one of six children in a single-parent household in Myanmar, Ma Khin learned a thing or two about poverty. So when she decided to open a restaurant that trains homeless street kids to be chefs and waiters, she knew she would be throwing herself into a tricky role. “The children on the streets have psychological issues,” the former tour guide says. “Sometimes we have children with criminal records. Sometimes we have thieves....on the streets, they steal in order to fill their stomachs.”

Still, Ma Khin's premise was sound; the restaurant, named LinkAge, has persevered. And Ma Khin is just one of twenty entrepreneurs being celebrated for working to uplift Asian communities, by Channel NewsAsia’s Ch...

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When Bob Charland learned he had a cyst in his brain as well as a tumor in his frontal lobe, it didn't come as a complete surprise. He already suffered from memory loss, tremors and severe headaches. But when the doctors told him the illness would eventually kill him, the surprise was how he reacted to the news.

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